Three-dimensional reconstructions (a–d, h, j) of a penis of an adult wild-type mouse treated neonatally with DES as described above. The 3DRs are presented in a variety of orientations with accompanying tissue sections (e–g, k). The patterns of epithelial-surfaced mesenchymal processes denoted in light and dark blue, red, turquoise, magenta and green are vastly different from that seen in untreated wild-type mice (compare with SEMs in Figs. 1–3).