Table 3.
Adjusted RRRs of Refusal or Contraindication
| Treatment and Characteristic | Refusal |
Contraindication |
||
|---|---|---|---|---|
| RRR | 95% CI | RRR | 95% CI | |
| Curative surgery for stage I/II NSCLC* | ||||
| Age, years | ||||
| < 55 | Reference | Reference | ||
| 55-64 | 1.99 | 0.44 to 9.07 | 1.71 | 0.95 to 3.10 |
| 65-79 | 3.85 | 0.95 to 14.54 | 2.50 | 1.38 to 4.54 |
| ≥ 80 | 16.39 | 3.64 to 73.83 | 6.62 | 3.37 to 13.02 |
| Race | ||||
| White | ||||
| None/mild/moderate comorbidity | Reference | Reference | ||
| Severe comorbidity | 1.18 | 0.60 to 6.01 | 2.12 | 1.54 to 2.91 |
| Black | ||||
| None/mild/moderate comorbidity | 2.40 | 1.25 to 4.64 | 1.78 | 1.20 to 2.65 |
| Severe comorbidity | 4.74 | 2.29 to 10.12 | 4.56 | 3.06 to 6.92 |
| Other | ||||
| None/mild/moderate comorbidity | 0.99 | 0.11 to 9.02 | 1.37 | 0.54 to 3.49 |
| Severe comorbidity | 2.18 | 0.75 to 11.20 | 3.49 | 2.08 to 6.40 |
| Marital status | ||||
| Not married/living with partner | Reference | Reference | ||
| Married/living with partner | 0.53 | 0.31 to 0.90 | 0.78 | 0.60 to 1.02 |
| Residence | ||||
| Urban | Reference | Reference | ||
| Rural | 1.22 | 0.70 to 2.10 | 1.04 | 0.78 to 1.40 |
| Stage | ||||
| I | Reference | Reference | ||
| II | 0.25 | 0.14 to 0.46 | 0.61 | 0.46 to 0.81 |
| Adjuvant chemotherapy for resected stage II/IIIA NSCLC | ||||
| Age, years | ||||
| < 55 | Reference | Reference | ||
| 55-64 | 0.79 | 0.15 to 4.19 | 0.63 | 0.22 to 1.81 |
| 65-79 | 1.43 | 0.27 to 7.52 | 0.80 | 0.25 to 2.57 |
| ≥ 80 | 19.54 | 1.34 to 284.41 | 6.48 | 0.58 to 71.82 |
| Race | ||||
| White | Reference | Reference | ||
| Black | 1.24 | 0.39 to 3.89 | 1.21 | 0.46 to 3.16 |
| Other | 1.66 | 0.29 to 9.47 | 0.62 | 0.07 to 5.35 |
| Marital status | ||||
| Not married/living with partner | Reference | Reference | ||
| Married/living with partner | 0.71 | 0.29 to 1.71 | 1.56 | 0.82 to 2.96 |
| Residence | ||||
| Urban | Reference | Reference | ||
| Rural | 1.07 | 0.43 to 2.64 | 0.94 | 0.49 to 1.82 |
| Therapy for advanced disease | ||||
| Age, years | ||||
| < 55 | Reference | Reference | ||
| 55-64 | 1.82 | 0.72 to 4.63 | 0.82 | 0.52 to 1.27 |
| 65-79 | 4.49 | 1.72 to 11.70 | 1.44 | 0.92 to 2.26 |
| ≥ 80 | 10.42 | 3.67 to 29.60 | 3.88 | 2.29 to 6.57 |
| Race | ||||
| White | Reference | Reference | ||
| Black | 1.19 | 0.74 to 1.92 | 0.96 | 0.75 to 1.23 |
| Other | 1.70 | 0.43 to 6.64 | 0.88 | 0.33 to 2.31 |
| Marital status | ||||
| Not married/living with partner | Reference | Reference | ||
| Married/living with partner | 0.74 | 0.54 to 1.01 | 0.76 | 0.62 to 0.94 |
| Residence | ||||
| Urban | Reference | Reference | ||
| Rural | 1.02 | 0.66 to 1.59 | 0.83 | 0.66 to 1.06 |
| Cancer type | ||||
| SCLC | Reference | Reference | ||
| NSCLC | 11.28 | 4.30 to 29.57 | 5.94 | 3.69 to 9.55 |
NOTE. Results not shown for no treatment without documented reason.
Abbreviations: NSCLC, non–small-cell lung cancer; RRR, relative risk ratio; SCLC, small-cell lung cancer
*
Model adjusted for interaction between race and comorbidity.