Table 2.
Odds Ratio (OR) and 95% Confidence Interval (CI) for Placental Abruption in Relation to Categories of Maternal Whole Blood Mitochondrial DNA Copy Numbers
| Whole Blood Mitochondrial DNA Copy Number | Placental Abruption Cases (N = 233) | Controls (N = 238) | Unadjusted OR (95% CI) | Adjusted OR* (95% CI) | Adjusted OR** (95% CI) |
|---|---|---|---|---|---|
| Quartile 1 (<179.5) | 58 | 59 | 1.00 (reference) | 1.00 (reference) | 1.00 (reference) |
| Quartile 2 (179.5-249.8) | 45 | 60 | 0.76 (0.45-1.30) | 0.85 (0.47-1.51) | 0.89 (0.49-1.63) |
| Quartile 3 (249.9-336.8) | 55 | 59 | 0.95 (0.57-1.59) | 0.99 (0.56-1.73) | 0.97 (0.54-1.75) |
| Quartile 4 (≥336.9) | 75 | 60 | 1.27 (0.77-2.09) | 1.51 (0.88-2.59) | 1.54 (0.88-2.70) |
| P-value for linear trend | 0.23 | 0.09 | 0.11 | ||
| Quartiles 1-3 (<336.9) | 158 | 178 | 1.00 (reference) | 1.00 (reference) | 1.00 (reference) |
| Quartile 4 (≥336.9) | 75 | 60 | 1.41 (0.95-2.10) | 1.60 (1.04-2.46) | 1.61 (1.03-2.52) |
*
Adjusted for maternal pre-pregnancy body mass index, no prenatal care and gestational age at delivery.
**
Adjusted for maternal pre-pregnancy body mass index, no prenatal care and gestational age at delivery and preeclampsia status.