Table 4.

HLA-DRB1. HLA-DQA1. HLA-DQB1 African American haplotypes, in 225 African American cases and 461 African American controls with complete genotypes at all three genes

Haplotype	Frequency/%		Odds ratio [95% CI]
DRB1.DQA1.DQB1	Cases	Controls
0701.0301.0202	3.1	0.8	1.93 [0.68–5.48]	5.28 [1.77–15.81]
0701.0302.0202	2.0	0.4
04.0302.0302	4.2	0.8	1.37 [0.47–4.06]	3.75 [1.25–11.31]
0301.0501.0201	18.9	5.1	1.00 (reference)	2.73 [1.52–4.91]
08.0401.0402	2.2	0.8
04.0301.0302	9.3	3.3	0.72 [0.37–1.37]	1.96 [0.97–3.92]
0901.0302.0202	2.7	0.3
0901.0301.0202	2.9	1.8	0.53 [0.24–1.18]	1.44 [0.60–3.47]
0701.0201.0202	7.3	6.4	0.37 [0.20–0.66]	1.00 (reference)
13.0102.05	2.4	2.7	0.32 [0.13–0.78]	0.87 [0.35–2.17]
01.0101.05	5.6	6.2	0.29 [0.16–0.52]	0.78 [0.40–1.54]
13.0102.06	4.2	4.7	0.26 [0.14–0.50]	0.72 [0.35–1.47]
13.0505.0301	1.5	1.7	0.28 [0.09–0.87]	0.77 [0.23–2.53]
04.0301.0301	0.9	1.3
1001.0101.05	2.2	3.1	0.20 [0.09–0.47]	0.56 [0.23–1.33]
11.0505.0319	2.4	3.9	0.22 [0.10–0.45]	0.59 [0.26–1.32]
08.0401.0319	2.9	4.0	0.21 [0.09–0.47]	0.57 [0.24–1.34]
13.0103.06	2.7	3.9	0.18 [0.07–0.41]	0.48 [0.19–1.18]
13.0201.0202	0.9	1.8
13.0505.0319	0.3	1.0
14.0101.05	0.7	1.7
11.0102.05	1.1	1.4	0.14 [0.04–0.43)	0.38 [0.12–1.18]
11.0102.0602	2.0	4.5	0.13 [0.05–0.30)	0.35 [0.14–0.86]
16.0102.05	0.7	1.5
1501.0102.0602	1.1	1.8	0.13 [0.03–0.45]	0.34 [0.09–1.27]
1503.0102.0602	4.0	11.1	0.11 [0.05–0.22]	0.30 [0.14–0.62]
0302.0401.0402	1.8	6.4	0.09 [0.04–0.22]	0.25 [0.10–0.64]
11.0505.0301	0.9	3.6	0.08 [0.03–0.23]	0.22 [0.07–0.64]
12.0101.05	0.9	3.4	0.07 [0.02–0.19]	0.19 [0.06–0.55]
Rares			0.26 [0.16–0.41]	0.70 [0.41–1.20]

The study is underpowered to detect rare effects, therefore only haplotypes with a combined frequency > 1% are listed and only those with a frequency > 1.5% are used to calculate odds ratios and 95% confidence intervals.