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. 2011 Nov;28(3):435–450. doi: 10.1159/000335106

Fig. 3.

Fig. 3

Pendrin-mediated Cl−/Cl− exchange is pH-insensitive in oocytes. A. 36Cl− efflux from 5 pendrin-expressing oocytes subjected to sequential Cl− baths at pHo 6.0 and 8.5. B. Mean efflux rate constants for 36Cl−(i)/Cl−(o) exchange at pHo 6.0 and 8.5 (n=5). C. 36Cl− efflux from 9 pendrin-expressing oocytes into an initial bath containing 56 mM NaCl and 40 mM Na butyrate, followed by butyrate substitution with 40 mM Na gluconate, and then by a brief exposure to DIDS (D). D. Mean efflux rate constants for 36Cl−(i)/Cl−(o) exchange in the presence and absence (pH 7.4) of 40 mM butyrate (n=9).