Skip to main content
. Author manuscript; available in PMC: 2013 Jul 12.
Published in final edited form as: J Immunol. 2011 Dec 21;188(3):1360–1370. doi: 10.4049/jimmunol.1101660

Figure 10. Th17 cells display plasticity in vivo by restoring both IL-17 and IFN-γ populations in brain abscesses of TCR αβ KO mice.

Figure 10

CD3+CD4+ T cells were recovered by FACS from brain abscesses of WT or TCR αβ KO mice receiving Th1 or Th17 adoptive transfer, whereupon T cells were stimulated immediately ex vivo with PMA + ionomycin for 3 h and stained for IL-17 and IFN-γ. Significant differences between the percentages of CD4+ IL-17 or IFN-γ positive cells in WT versus TCR αβ KO mice are denoted by asterisks (*, p < 0.05). Results represent the mean ± SEM combined from three independent experiments.