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Increased MMP activity in vivo in xenografts containing CAMs. (A) In BALB/c nu/nu mice, MMP activity revealed by FMT imaging of MMPSense 750 FAST is increased in xenografts of gastric cancer MKN45 cells containing two different CAMs compared with MKN45 cells alone. (B) Representative FMT images of mice with xenografts of MKN45 cells alone (top row), MKN45 cells + CAM2 (middle row), and MKN45 cells + CAM1 (bottom row).
