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Minimum fungicidal and bactericidal activity of compounds 1-4.
| Compound | MFC/MBC (μg/mL)
|
||||
|---|---|---|---|---|---|
| C. neoformans | E. coli | MRS | A. fumigatus | M. intracellulare | |
| 1 | 2.5 | 5.0 | - | - | 10.0 |
| 2 | 20.0 | - | - | - | - |
| 3 | 2.5 | 10.0 | - | - | - |
| 4 | 10.0 | - | - | - | - |
| Amphotericin B | 2.5 | NT | NT | 2.5 | NT |
| Ciprofloxacin | NT | 0.031 | 1.00 | NT | - |
- = Not Active; NT = Not Tested; MFC/MBC (Minimum Fungicidal/Bactericidal Concentration) is the lowest test concentration that kills the organism.
