Figure 8. Arrangement of capsid targeting genes in phages.

Sets of capsid genes relevant to capsid targeting are diagrammed here and further explained in the text. Genes are shown as rectangles, with overlapping genes shown as smaller rectangles within a larger one, and with the gene name or function within the rectangle. Abbreviations: mMCP, mature part of major capsid protein; Δ, delta domain of major capsid protein; p’ase, protease; scaf, scaffolding protein; Flp, ferritin-like protein; other symbols are defined in the figure. In (e) and (f), plausible ribosome binding sites are present upstream of internal Met codons that would allow the translation of a proposed shorter protein containing only a delta-domain like segment and the mature portion of major capsid protein, invoking a co-assembly mechanism like that found in λ, Mu, and HSV-1. References for these gene arrangements are as follows: (a) HK97^8;20(b) Thermoga maritima⁵⁷(c)Pyrococccus furiosus^57;58;59 (d) P2^18;61;98 (e) c2⁸⁴ (f) Gifsy2^85;86 (g) λ^63;64;69 (h) HSV-1^{66; 67; 68; 99} (i) T4 ^{51; 52; 70; 73; 77}