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. 2013 May;94(Pt 5):917–932. doi: 10.1099/vir.0.049296-0

Table 1. Summary of the evidence for and against the hypothesis that the persistent residual viraemia in HAART-treated patients originates from a single source.

Persistent viraemia originated from one source (resting T-cells)     References
• Viral genomes recovered from persistent viraemia show little variation Bailey et al. (2006); Joos et al. (2008); Ruff et al. (2002)
• HAART intensification does not reduce residual viraemia Dinoso et al. (2009b); Gandhi et al. (2010); Hatano et al. (2011); McMahon et al. (2010)
Multiple sources contribute to persistent viraemia
• Persistent HIV-1 infection has been found within different parts of the body See text
• Viral sequences distinct from those isolated from resting T-cells are found Bailey et al. (2006); Brennan et al. (2009); Sahu et al. (2009)
• HAART intensification increased 2-LTR circles from PBMCs Buzón et al. (2010)
• HAART intensification reduced HIV-1 RNA within the ileum Yukl et al. (2010)