Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Proposed mechanism for the downregulation of GADD45α expression by HCV NS5A, contributing to cell survival in human HCC cells. The NF-κB and PI3K–Akt pathways cooperatively influence HCV NS5A-mediated downregulation of p53 and subsequently inhibit GADD45α expression. The resulting GADD45α reduction contributes to cell proliferation.
