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K7 is a virulence factor in the i.d. infection model. C57BL/6 mice (n = 5 per group) were mock-infected or infected i.d. with 1×104 p.f.u. per ear of the indicated viruses into both ears. Lesion sizes were measured daily and data are expressed as mean±sem. Infection with vΔK7 induced a smaller lesion compared with vK7 and vK7-rev (*, P<0.05).
