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Survival of mice after vaccination with MP-12 or rMP12-TOSNSs. Kaplan−Meier survival curves of outbred CD1 mice (5–6 weeks old) s.c. vaccinated with 1×105 p.f.u. of MP-12 or rMP12-TOSNSs (a), those of BALB/c mice (4 weeks old) i.p. vaccinated with 1×103 (b) or 1×105 p.f.u. (c) of MP-12 or rMP12-TOSNSs, and those of C57BL/6 mice (4 weeks old) i.p. vaccinated with 1×103 (d) or 1×105 p.f.u. (e) of MP-12 or rMP12-TOSNSs.
