Table 4.
The incidence of adverse effects and the V14
| Symptomatic brain edema | V14 <5.0 cm3 | V14 ≥5.0 cm3 | P value |
|---|---|---|---|
| Number of lesions | 1/72 | 5/87 | 0.07 |
| Median tumor volume (cm3) (range) | 3.3 (0.04–18.9) | 8.5 (1.5–25.9) | |
| Median V14 (cm3) (range) | 2.9 (0.01–4.9) | 6.6 (5.0–31.5) | |
| Follow-up period (month) | 1–30 | 1–30 | |
| No. patients survived more than 12 months | 9 | 14 | |
| Radiation necrosis required surgery | V14 <7.0 cm3 | V14 ≥7.0 cm3 | P value |
| Number of patients | 0/124 | 3/35 | 0.04 |
| Median tumor volume (cm3) (range) | 6.0 (0.04–18.9) | 9.6 (3.4–25.9) | |
| Median V14 (cm3) (range) | 4.7 (0.01–6.9) | 8.5 (7.0–31.5) | |
| Follow-up period (month) | 1–30 | 1–26 | |
| No. patients survived more than 12 months | 16 | 7 | |