Fig. 4.

GBV-Ccpz E2 protein expression inhibits diverse HIV isolates. Jurkat cells expressing GBV-Ccpz E2 (1–331 aa) inhibited all six CXCR4-tropic HIV isolates studied. Strains are identified by their clade (B, A or D) or their resistance to T-20 (T) and their derivation as clinical (C) or laboratory (L)-derived strains (see Table 1). HIV inhibition rates are represented as a percentage of the reduction of HIV p24 antigen compared with FS. *, Inhibition was significantly less than other isolates (P<0.001) except isolate B-T2.