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Epigenetic alterations were described in eight studies of penile carcinoma (PeCa). Aberrant DNA methylation pattern of DAPK, FHIT, MGMT, CDKN2A, RARβ, RASSF1A, TSP-1, and RUNX3 and alteration in the expression levels of histones were events related with this disease. In special, CDKN2A gene was evaluated in six studies.
