Table 3.

Multivariate Cox proportion hazard model for cancer-specific and overall survival in ccRCC patients.

		Hazard Ratio (95% CI)
Variable	Categories	Overall survival	p-value	Cancer specific survival	p-value
Age	±median	1.88 (1.25–2.83)	0.002	1.18 (0.69–2.00)	0.56
T-stage	T1/2 vs. T3/4	2.63 (1.63–4.23)	<0.0001	4.30 (2.03–9.10)	<0.0001
N-stage	N0 vs. N1/2	1.59 (0.75–3.42)	0.23	1.89 (0.83–4.32)	0.13
M-stage	M0 vs. M1	3.43 (2.09–5.62)	<0.0001	4.58 (2.46–8.52)	<0.0001
Nuclear Grade	G1/2 vs. G3/4	0.98 (0.54–1.80)	0.96	1.37 (0.69–2.73)	0.37
Tumor Necrosis	yes vs. no	1.23 (0.83–1.84)	0.3	1.65 (0.94–2.90)	0.08
Sarcomatoid Differentiation	yes vs. no	1.63 (0.83–3.20)	0.15	1.62 (1.68–3.45)	0.16
β-catenin Score cytoplasm tumor	±mean	1.00 (0.55–1.84)	0.99	0.88 (0.43–1.83)	0.75