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. 2013 May 27;14(6):11171–11189. doi: 10.3390/ijms140611171

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© 2013 by the authors; licensee MDPI, Basel, Switzerland

This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).

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Mean fold changes of target genes of exo-miRNAs and endo-miRNAs, according to the expression levels. Differential fold changes (log₂) of target gene expression levels of exo-miRNAs (A) and endo-miRNAs (B) and the number of the top 20 endo-miRNA target sites (C), according to the expression levels of exo-miRNA targets. The averaged numbers of exo-miRNA target sites are 130, 217, 237 and 215 (A), and those of endo-miRNA target sites are 92, 164, 176 and 202 (B) in the 3′ UTRs of genes with differential fold changes of 0~7, 7~9, 9~11 and 11~.