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. 2013 Mar 20;12(4):424–437. doi: 10.1111/gbb.12029

Figure 3. Significant genome-wide QTL for behaviors in the visual-cliff avoidance test.

Figure 3

Phenotypic distribution of DO mice for (a) ratio of distance traveled in the bottom area. Solid colored bar below histograms represent phenotype ranges (min–max) of each progenitor strain. Significant genome-wide QTL for (b) bottom distance traveled. Horizontal lines represent permuted significance thresholds as follows, solid red line (significant, P < 0.05), solid (highly suggestive, P < 0.10) and dashed orange lines (suggestive, P < 0.63). Allelic effect plots of eight coefficients of the QTL mixed model representing the effect of each founder haplotype on phenotype. (c) An increasor NZO/H1LtJ allele and a decreasor 129S1/SvlmJ allele on Chromosome 14 were associated with distance traveled in the bottom of the visual-cliff. Dashed line is the maximum LOD −1.5, defining the 95% support interval of the QTL.