Fig. 3.
Effect of nitric oxide synthase inhibitor NG-nitro-L-arginine methyl ester (L-NAME) on the concentration of (A) interleukin-6 (IL-6) and (B) interleukin-10 (IL-10) in the media collected from HK-2 proximal tubule epithelial cells after activation with lipopolysaccharide (LPS, 10μg/ml) and/or AT2R agonist (C21, 1μmol/L) for 24 hours. Cytokine concentrations in media were measured by ELISA. Data are represented as mean ± SEM. * indicates p<0.05 vs respective control (A), # indicates p<0.05 vs LPS+C21 (B) treated HK-2 cells (n=5). ND indicates not detected.