Fig. 7.
Renal morphometry (A) Periodic Acid Schiff (PAS) stained sections from the kidney cortex of lean (L, upper panel) and obese (O, lower panel) Zucker rats after 2 weeks treatment with vehicle (V), AT2R antagonist PD123319 (PD), AT2R agonist (C21) and both PD123319+C21 (PD+C21). (B) Semi-quantitative mesangial matrix expression (MME) score from PAS stained sections. An average MME score was obtained from analysis of 30 glomeruli per rat. Data are mean ± SEM (n=6). * indicates p<0.05 vs lean vehicle treated, # indicates p<0.05 vs obese vehicle treated rats (400x magnification).