Table 3.

Associations Between SHFM Scores and EQ-5D Health Utilities Over Time

	Base-Case Analysis		Sensitivity Analysis*
	Effect (95% CI)	P Value	Effect (95% CI)	P Value
Model 1: SHFM Score Modeled as Continuous Variable
Intercept	0.8227 (0.8170 to 0.8284)	< .001	0.8170 (0.8102 to 0.8238)	< .001
Change in EQ-5D utilities per 1-unit increase in SHFM score	–0.0300 (–0.0382 to –0.0215)	< .001	–0.0405 (–0.0505 to –0.0305)	< .001
Change in EQ-5D utilities per year	–0.0015 (–0.0035 to 0.0006)	0.16	–0.0164 (–0.0195 to –0.0134)	< .001
Additional change in EQ-5D utilities per year per 1-unit increase in SHFM score	–0.0062 (–0.0095 to –0.0030)	<.001	–0.0223 (–0.0271 to –0.0176)	< .001
Model 2: SHFM Score Modeled as Categorical Variable
Intercept	0.8300 (0.8143 to 0.8457)	< .001	0.8277 (0.8089 to 0.8466)	< .001
SHFM score group
≤ –1	[Reference]	—	[Reference]	—
0	–0.0021 (–0.0193 to 0.0151)	0.81	–0.0045 (–0.0251 to 0.0162)	0.67
1	–0.0409 (–0.0596 to –0.0222)	< .001	–0.0528 (–0.0753 to –0.0303)	< .001
≥ 2	–0.0532 (–0.0849 to –0.0217)	0.001	–0.0910 (–0.1287 to –0.0533)	< .001
Change in EQ-5D utilities per year	0.0035 (–0.0022 to 0.0092)	0.23	0.0013 (–0.0072 to 0.0098))	0.77
Additional Change in EQ-5D Utilities per Year by SHFM Score group
SHFM score group
–1	[Reference]	—	[Reference]	—
0	–0.0050 (–0.0112 to 0.0013)	0.12	–0.0193 (–0.0285 to –0.0010)	< .001
1	–0.0106 (–0.0175 to –0.0037)	0.0025	–0.0342 (–0.0444 to –0.0241)	< .001
2	–0.0197 (–0.0329 to –0.0065)	0.0035	–0.0724 (–0.0909 to –0.0538)	< .001

^*Results from the regression model including 0 utility weights after patients died.