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. 2013 Jul 12;8(7):e69521. doi: 10.1371/journal.pone.0069521

Figure 1. Effect of endothelial cells on cytokine production in PBMC/iRBC co-cultures.

Figure 1

A. Significant alterations in IFN-γ and IL-10 (mRNA and protein) production in PBMC/iRBC (P. falciparum strain 3D7) co-culture in the presence of endothelial cells (HBEC-5i). B. TNF protein production was significantly decreased in the presence of HBEC-5i. uRBC =  unparasitised red blood cells. Control  =  no PBMC, uRBC or iRBC. Columns and horizontal bars represent means ± SEM of nine experiments. Two-way ANOVA showed significant differences among the groups (*p<0.05; ***p<0.001), identified using the Bonferroni post hoc test.