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. 2013 Jul 12;8(7):e69521. doi: 10.1371/journal.pone.0069521

Figure 3. HBEC-dependent induction of ICAM-1 and CXCL10 in tripartite co-cultures is inhibited by IFN-γ neutralising antibody.

Figure 3

A. IFN-γ neutralising antibody inhibits ICAM-1 mRNA induction in tripartite cultures. B. IFN-γ neutralising antibody inhibits expression of CXCL10 mRNA and protein in the tripartite cultures. uRBC  =  unparasitised red blood cells. Control  =  no PBMC, uRBC or iRBC. Columns and horizontal bars represent means ± SEM of three experiments. Two-way ANOVA showed that the values contained significant differences among the groups (***p<0.001), using ANOVA and the Bonferroni post hoc test.