Table 1.
Features of leukocytoclastic vasculitis
| DISEASE | IMPORTANT FEATURES |
|---|---|
| Large-vessel | |
| • Takayasu arteritis | Age < 50 y, claudication, blood pressure difference of > 10 mm Hg between arms |
| • Giant cell arteritis | Age > 50 y, unilateral headache, high ESR, jaw claudication |
| Medium-vessel | |
| • Polyarteritis nodosa | Livedo reticularis, ulcers, SC nodules, high blood pressure, testicular pain |
| • Kawasaki disease | Occurs in young children; fever, cervical lymphadenopathy, coronary artery aneurysm |
| Small-vessel | |
| • Microscopic polyangiitis | Glomerulonephritis, alveolar hemorrhage, positive test result for p-ANCA |
| • Wegener granulomatosis | Ulceration, SC nodules, upper and lower respiratory tract and kidney involvement, positive test result for c-ANCA |
| • Churg-Strauss syndrome | Ulceration, SC nodules, asthmalike symptoms, lung and kidney involvement, positive test result for p-ANCA |
| • Henoch-Schönlein purpura | Age < 20 y; palpable purpura; kidney, bowel, and joint involvement |