Figure 2.

Oligodendrocytes, but not astrocytes or microglia, express p75 after contusion injury in the spinal cord. A–F, A coronal view of p75 expression among CC1⁺ oligodendrocytes at 14 d after injury. Boxed areas in A, C, and E are shown in a higher magnification in B, D, and F. Arrows indicate p75⁺CC1⁺ oligodendrocytes. Note that p75 is also expressed in the fasciculus gracilis (gr in E, G). Scale bars: (for A, C, E) 75 μm; (for B, D, F) 18 μm; (for G) 7 μm. H, Invading Schwann cells in the dorsal root entry zone (DREZ). A boxed area is shown in a high magnification. Scale bar, 7 μm. Note that p75Schwann cells appear myelinating NFaxons. I, GFAP⁺ astrocytes do not express p75. Note that astrocytic processes are in close contact with p75⁺ fibers in the fasciculus gracilis. Scale bar, 14 μm. J, OX42⁺ microglia do not express p75. Scale bar, 14 μm. The experiments were repeated >5 times, and representative images are shown.