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. Author manuscript; available in PMC: 2013 Jul 12.
Published in final edited form as: J Immunol. 2011 Sep 30;187(9):4705–4713. doi: 10.4049/jimmunol.1100794

FIGURE 4. Structure of Vα14-Vβ8.2 NKT TCRs in complex with CD1d-α-C-GalCer.

FIGURE 4

(A)Vα14-Vβ8.2 NKT TCR in complex with CD1d-α-C-GalCer. α-C-GalCer, blue; CD1d heterodimer, grey; Vα14, cyan; Vβ8.2, green. CDR1α, purple; CDR3α, yellow; CDR1β, teal; CDR2β, ruby; CDR3β, not modelled. B, Vα14-Vβ8.2 NKT TCR in complex with CD1d-α-GalCer. α-GalCer, magenta; CDR3β, orange; CD1d, Vα14, Vβ8.2, CDR1α, CDR3α, CDR1β, CDR2β colour coding as in A. C, Footprint of Vα14-Vβ8.2 on the surface of CD1d-α-C-GalCer. α-C-GalCer is shown in spheres. CD1d, α-C-GalCer and CDR loops colour coding as in A. D, footprint of Vα14-Vβ8.2 on the surface of CD1d-α-GalCer. CD1d, α-GalCer and CDR loops colour coding as in A and B.