Table 6.
Neuropsychological assessment results in Patients no. 3 and no. 4
| Patient no. 3 | Patient no. 4 | |||||
|---|---|---|---|---|---|---|
|
| ||||||
| Age: years/ months (years since onset) | 50/0 (6) | 52/0 (8) | 53/2 (9) | 48/0 (0) | 49/11 (1) | 51/0 (2) |
|
| ||||||
| Global measures | ||||||
| MMSE (max. 30 points) | 16 | 4 | 1 | 30 | 29 | 29 |
| BDRS (max. 28 points) | NA | 9.5 | 18 | NA | 0 | 0 |
| ACE-R global score (max.100 points) | NA | 22 | NA | NA | NA | |
|
| ||||||
| Executive function | ||||||
| WCST - Categories attained (max. 6) | NA | NA | NA | NA | 6 | NA |
| FAB (max. 18 points) | 3 | 1 | NA | 18 | 18 | 17 |
| Stroop test (interference:% of errors) | NA | NA | NA | NA | 1.02 | 2.04 |
| Luria’a alternate design (% of errors) | 0 | DD | DD | NA | 3 | NA |
| Similarities from WAIS-R (Scaled Score) | NA | NA | NA | 15 | 13 | 14 |
|
| ||||||
| Attention and memory | ||||||
| Digit Span forward - max. span | 4 | 4 | 3 | 4 | 6 | 5 |
| Digit Span backward - max. span | 0 | 0 | 0 | 4 | 4 | 4 |
| Block span forward- max. span | NA | NA | NA | NA | 6 | 6 |
| Block span backward- max. span | NA | NA | NA | NA | 4 | 5 |
| BVRT-version F (max. 15) | NA | NA | NA | NA | 13 | 15 |
| TMT A (T-score) | DD | DD | NA | 40 | 47 | 42 |
| TMT B (T-score) | NA | NA | NA | 65 | 48 | 48 |
| TMT B-A (T-score) | NA | NA | NA | 25 | 1 | 6 |
| TMT B (errors) | NA | NA | NA | 0 | 1 | 0 |
| 10 word-list learning | 3,4,4,5,5,6,5,6 | NA | NA | 4,5,9,9,10,10,10 | NA | NA |
| 10 word-delayed recall | 3 | NA | NA | 9 | NA | NA |
| 10 word-delayed recognition | 8 | NA | NA | 10 | NA | NA |
| AVLT-learning curve | NA | NA | NA | NA | 6,10,13,14,15 | 7,12,12,14,15 |
| AVLT-recognition | NA | NA | NA | NA | 15 | 15 |
| AVLT-delayed recall | NA | NA | NA | NA | 15 | 14 |
| AVLT-retention (%) | 50% | NA | NA | NA | 100% | 93% |
| AVLT-sum of intrusions | NA | NA | NA | NA | 3 | 0 |
| AVLT-delayed recognition | NA | NA | NA | NA | NA | 15 |
| Rey/ Taylor CFT-after delay (%) | 125 | 105 | NA | 49 | 97 | 94 |
| Information (WAIS-R) - Scaled Score | NA | NA | NA | NA | 14 | 14 |
|
| ||||||
| Visuospatial functioning | ||||||
| CFT-Rey/Taylor-copy (raw score) | 16 | 9.5 | 2 | 35 | 33 | 36 |
|
| ||||||
| Verbal fluency | ||||||
| semantic fluency trials (animals, plants/ fruit and vegetables) | 11 | 1 | NA | 33 | 48 | 49 |
| phonemic fluency trials ( K”, P”) | NA | 0 | NA | NA | 17 | 21 |
| (“P”, “W”) | 2 | NA | NA | 13 | NA | NA |
|
| ||||||
| Planning | ||||||
| Tower of London-total move score, SS | NA | NA | NA | 112 | NA | 122 |
| Tower of Toronto- total score | NA | NA | NA | NA | 11 | 14 |
ACE-R, Addenbrooke Cognitive Examination-Revised; AVLT, Auditory Verbal Learning Test; BDRS, Blessed Dementia Rating Scale; BVRT, Benton Visual Retention Test; CFT, Complex Figure Test; DD, discontinued; FAB, Frontal Assessment Battery; MMSE, Mini Mental State Examination; NA, not available; SS, standardized score, TMT, Trail Making Test; WAIS-R, Wechsler Adult Intelligence Scale-Revised; WCST, Wisconsin Card Sorting Test