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Figure 1. Secondary structure models of (A) TLDaa, (B) TLD-Haa and (C) full-length ectmRNA. The TLD parts of the A. aeolicus and E. coli models are very similar in sequence. An arrow stresses the position of the ribothymidine m5U (labeled T for simplification) (i.e. 38 in TLDaa, 121 in TLD-Haa and 341 in ectmRNA). The second methylated uridine observed in TLD-Haa, as explained in text, is most probably U97.
