Figure 1.
Effect of HDAC inhibition on NB growth and cell cycle in vitro. (A) In vitro cell proliferation was examined by MTS colorimetric assays. NBL-W-N cells were grown for 1–3 days in the presence or absence of VPA with varying concentrations as indicated. (B) In vitro cell proliferation was examined by MTS colorimetric assays. LA1-55n cells were grown for 1–3 days in the presence or absence of VPA with varying concentrations as indicated. (C) BrdU incorporation assay was performed in LA1-55n cells treated with various concentrations of VPA for 1 day. (D) BrdU incorporation assay was performed in LA1-55n cells treated with various concentrations of TSA for 1 day. * p<0.05 compared to control