Table 1.
IC50 values for anticancer drugs in SGC7901/DDP cells
| Doxorubicin (μg/mL) | 5-fluorouracil (μg/mL) | Cisplatin (μg/mL) | |
| SGC7901/DDP + siRNA-CDX2 | 0.12 ± 0.05a | 0.52 ± 0.13a | 0.82 ± 0.13a |
| SGC7901/DDP + siRNA-NC | 0.33 ± 0.08 | 4.10 ± 1.25 | 2.81 ± 0.50 |
| SGC7901/DDP | 0.39 ± 0.15 | 4.05 ± 1.44 | 3.28 ± 1.03 |
IC50 values were evaluated by MTT assay. Each experiment was conducted in triplicate. Data are expressed as means ± SD. One-way analysis of variance followed by Dunnett’s multiple comparison tests revealed statistical differences.
a
P < 0.05 for SGC7901/DDP + small interfering RNA (siRNA)-CDX2 cells vs SGC7901/DDP + siRNA-NC cells and SGC7901/DDP cells.