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. 2013 Jul 10;14:140. doi: 10.1186/1471-2369-14-140

Table 1.

Differential diagnosis of hyponatremia

Hyponatremia
 
Hypervolemic
Euvolemic
Hypovolemic
TBW
++
+
+
+
-
_
TBNa
+
N
N
N
-
-
Urine Na
-
+
N/+
-
-
-
Urine Osm
+
+
+
-
+
+
Edema
+
-
-
-
-
-
BP
-
N
N
N
-
-
Diuresis
-/N
-/N
N
+
_
+
Possible diagnoses
CHF
SIAD
Drugs
Primary Polydipsia
NON renal Losses:
Renal Losses:
 
Cirrhosis
 
Nausea
 
 
Diuretics
 
Nephrotic Syn.
 
Addison
 
Vomiting
C/RSWS
 
 
 
 
 
Diarrhea
 
          Sweating  

TBW: Total Body Water, TBNa: Total Body Sodium, BP: Blood Pressure, CHF: Chronic Heart Failure,

SIAD: Syndrome of Inappropriate Antidiuresis, C/RSWS: Cerebral Renal Salt Wasting Syndrome. N: Normal, +:elevated, -: reduced.