FIG. 5.

The C-terminal transmembrane peptide inhibits HCV RNA replication in Huh-7/replicon cells. Cells were treated with the peptides as in the experiments shown in Fig. 4. Total cellular RNA was analyzed for HCV and GAPDH RNA by real-time Taqman PCR. Relative HCV RNA copies per GAPDH RNA are presented. The RNA level in 1% DMSO-treated cells is represented as 100%. Experiments were repeated four times, and the average values for the experiments are shown.