Figure 3.

Time-dependent effects of Hb changes on the survival of cancer patients. Flexible parametric modeling framework was used to assess the effect by Hb changes on the overall survival of patients of (A) all cancers, (B) lung cancer, (C) breast cancer, (D) colorectal cancer, and (E) liver cancer. The analysis was adjusted for age, gender, ethnicity, tumor stage, tumor grade, chemotherapy, radiation therapy and surgery. Solid lines indicated hazard ratios and shaded areas showed the 95% confidence intervals. Dash lines represented the references.