FIG. 7.
Partial effect of IL-10 treatment on the IgG2a/IgG1 ratio in orally infected mice. BALB/c mice were infected either orally or in the FP with 3 × 107 PFU of reovirus/mouse. Orally infected mice received rIL-10 at 100 ng/dose (or PBS as vehicle where noted) every 12 h for the first 5 days postinfection, and serum antibody responses were determined 10 days following infection. Bars indicate the standard errors among groups of four mice. Representative data are from one of three independent experiments.