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. 2013 Jul 3;2(1):299. doi: 10.1186/2193-1801-2-299

Table 4.

Expression of SDHA and SDHB according to HIF-1α expression status

Factors Nuclear HIF-1α Cytoplasmic HIF-1α
Negative n = 697 (%) Positive n = 24 (%) P-value Negative n = 717 (%) Positive n = 4 (%) P-value
Tumoral SDHA 0.247 0.518
 Negative 40 (5.7) 1 (4.2) 40 (5.6) 1 (25.0)
 Low 311 (44.6) 8 (33.3) 318 (44.4) 1 (25.0)
 High 346 (49.6) 15 (62.5) 359 (50.1) 50.0)
Stromal SDHA 0.423 1.000
 Negative 644 (92.4) 21 (87.5) 661 (92.2) 4 (100.0)
 Positive 53 (7.6) 3 (12.5) 56 (7.8) 0 (0.0)
Tumoral SDHB 0.926 0.032
 Negative 24 (3.4) 0 (0.0) 23 (3.2) 1 (25.0)
 Low 235 (33.7) 10 (41.7) 243 (33.9) 2 (50.0)
 High 438 (62.8) 14 (58.3) 451 (62.9) 1 (25.0)
Stromal SDHB 0.328 1.000
 Negative 621 (89.1) 20 (83.3) 637 (88.8) 4 (100.0)
 Positive 76 (10.9) 4 (16.7) 80 (11.2) 0 (0.0)

SDH succinate dehydrogenase.