Table 1.
Clinicopathologic features of patients with non-ccRCC versus unmatched patients with ccRCC
| Variable | Non-ccRCC (N=56) | ccRCC (N=751) | p value |
|---|---|---|---|
| Age in years (IQR) | 65 (57,75) | 64(56,72) | 0.42 |
| Tumor size cm (IQR) | 10.5 (8.0,15.0) | 9.3(7.5,12) | 0.02 |
| Gender | |||
| Female | 14 (25%) | 233 (31%) | 0.35 |
| Male | 42 (75%) | 518 (69%) | |
| Local symptoms at presentation | 45 (80%) | 655 (87%) | 0.14 |
| Constitutional symptoms at presentation | 25 (45%) | 358 (48%) | 0.66 |
| ECOG performance status | |||
| 0 | 33 (77%) | 525 (85%) | 0.14 |
| 1 | 6 (14%) | 66 (11%) | |
| 2 | 4 (9%) | 19 (3%) | |
| 3 | 0 (0%) | 10 (2%) | |
| Pathologic tumor stage | |||
| pT3a | 24 (43%) | 466 (62%) | 0.027 |
| pT3b | 23 (41%) | 205 (27%) | |
| pT3c | 4 (7%) | 39 (5%) | |
| pT4 | 5 (9%) | 41 (4%) | |
| pN+ at nephrectomy | 21 (38%) | 99 (13%) | <0.001 |
| M1 at nephrectomy | 16 (29%) | 210 (28%) | 0.92 |
| Tumor thrombus level | |||
| 0 | 28 (50%) | 488 (65%) | 0.27 |
| I | 9 (16%) | 88 (12%) | |
| II | 11 (20%) | 100 (13%) | |
| III | 4 (7%) | 40 (5%) | |
| IV | 4 (7%) | 35 (5%) | |
| Nuclear grade | |||
| 1 | 0 (0%) | 15 (2%) | 0.04 |
| 2 | 5 (9%) | 127 (17%) | |
| 3 | 31 (55%) | 451 (60%) | |
| 4 | 20 (36%) | 158 (21%) | |
| Coagulative tumor necrosis | 38 (68%) | 431 (57%) | 0.13 |
| Sarcomatoid differentiation | 14 (25%) | 68 (9%) | <0.001 |