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. Author manuscript; available in PMC: 2013 Jul 14.
Published in final edited form as: J Biochem Mol Toxicol. 2011 May 2;25(5):320–329. doi: 10.1002/jbt.20392

Figure 3.

Figure 3

Multidrug resistance-associated protein (Mrp) 1, 3-6 mRNA and protein expression in livers of wild-type (WT) and hepatocyte-specific Keap1-null (KO) mice. (A). mRNA expression of Mrp1, 3-6. Total RNA was isolated from liver and mRNA levels were quantified using branched DNA signal amplification assay. mRNA expression level is presented as mean RLU ± SEM (n = 4 animals). Asterisks (*) represent a statistical difference between WT and KO (p < 0.05). (B). Individual Western blots of Mrp1, 3, 4, and 5 in livers from WT and KO mice (protein loading amount 50 μg/lane, n = 4). (C). Quantification of Mrp1, 3, and 5 relative protein expressions in KO mice compared to WT. No quantification for Mrp4 because it is undetectable in WT livers. Asterisks (*) represent a statistical difference from corresponding WT (p < 0.05).