Table 2.
Differences in protein expression levels in synaptosome fractions between HA-NL1FL and HA-NL1ΔC mice
| Protein | % Δ | SEM | p value | Effect size | Cohen's d |
|---|---|---|---|---|---|
| HA-NL1ΔC | |||||
| NL1 | 198.43 | 5.73 | 0.0021** | 0.99 | 15.88 |
| NL3 | 108.73 | 0.94 | 0.1380 | 0.63 | 1.65 |
| NR1 | 111.18 | 5.12 | 0.1481 | 0.62 | 1.56 |
| NR2A | 104.31 | 0.27 | 0.1732 | 0.78 | 2.48 |
| NR2B | 125.34 | 2.46 | 0.0443* | 0.96 | 6.51 |
| GluR1 | 148.80 | 7.49 | 0.2250 | 0.83 | 2.98 |
| GluR2 | 116.56 | 4.04 | 0.1018 | 0.85 | 3.16 |
| PSD-95 | 109.92 | 0.87 | 0.1834 | 0.97 | 7.37 |
| PanShank | 94.61 | 8.89 | 0.7536 | −0.25 | −0.52 |
| Gephyrin | 96.73 | 1.17 | 0.1823 | −0.78 | −2.65 |
| PICK1 | 95.85 | 5.67 | 0.6600 | −0.37 | −0.79 |
| SAP97 | 73.14 | 18.44 | 0.0213* | −0.70 | −1.95 |
| SAP102 | 126.59 | 0.40 | 0.0316* | 0.99 | 44.66 |
| SNAP25 | 105.48 | 0.96 | 0.0065** | 0.92 | 4.65 |
| Synapsin1 | 112.16 | 1.78 | 0.0782 | 0.81 | 2.75 |
| VGLUT1 | 98.99 | 0.73 | 0.2849 | −0.52 | −1.22 |
Summary statistics for levels of all synaptic proteins analyzed from hippocampal synaptosome fractions from controls versus HA-NL1ΔC mice. Significance was determined with Student's t test,
*p < 0.05 and **p > 0.01, n = 4 animals in each group.