TABLE 4.

Classes of genes regulated by PRV-Be and HSV-1(F) infection

Functional class	No. of genes	PRV only	HSV only	PRV and HSV
Signaling	146	47	58	41
Metabolism	138	46	49	43
Cell adhesion	96	11	38	47
Cellular transport	85	37	20	28
Transcription factor	55	28	12	15
Neuronal	53	16	22	15
Stress response	49	21	15	13
Channels and transporters	42	7	19	16
Immunity	41	9	17	15
Kinase	38	15	10	13
Protein folding	36	15	14	7
Nucleus and nuclear matrix	34	13	14	7
Ribosomal proteins	25	20	2	3
Oncogenesis	24	10	5	9
Hormone related	22	5	5	12
Apoptosis	20	8	8	4
RNA-binding proteins	18	9	3	6
Cell cycle related	17	4	7	6
Cytokine or chemokine	15	6	7	2
Electron transport	21	5	9	7
Growth factor	12	0	7	5
Prostaglandin related	12	2	5	5
Peroxisome related	8	3	3	2
Translation	6	2	2	2
Unclassified	117	24	42	51
ESTs	419	158	137	124
Total	1,549	521	530	498