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. 2013 Jun 24;110(28):11499–11504. doi: 10.1073/pnas.1219852110

Fig. 6.

Fig. 6.

MiR-146b down-regulates TLR4-dependent production of proinflammatory cytokines. (A–H) Proinflammatory cytokine levels measured by ELISA in cell-free supernatants of THP-1 cells transduced with lentiviral vectors overexpressing miR-146b (pRRL-146b and its respective control) or a miR-146b sponge (miRzip-146b and its respective control) after stimulation with 1 µg/mL LPS. (I) CXCL10 levels measured by ELISA in cell-free supernatants collected under the same experimental conditions after stimulation with 10 ng/mL IFN-γ.