Fig. 2.

MR enterographic detection of active inflammation and fibrosis. Imaging is depicted from abnormal small bowel segments (arrows) in 2 subjects, the first demonstrates bowel wall T2 hyperintensity (a) early mucosal enhancement (b) and later progressive transmural enhancement (c) suggestive of active inflammation, while the second demonstrates bowel wall T2 hypointensity (e) and minimal wall enhancement (f) that does not increase with time (g) suggestive of fibrosis. Histological assessment of corresponding surgical excision specimens confirms the MR findings, with active inflammation characterized by neutrophilic invasion of the mucosal glands (d) and submucosal collagen deposition indicative of mural fibrosis (h).