Table 2.
MR enterographic assessment of Crohn's disease activity compared with histologic reference standard.
| Number of subjects | 21 |
| Total number of bowel segments | 53 |
| -Endoscopic biopsy | 16 |
| -Surgical resection | 37 |
| Bowel segment locations: | |
| -Small bowel upstream of TI | 12 |
| -Terminal ileum | 18 |
| -Cecum/ascending colon | 12 |
| -Transverse/descending colon | 8 |
| -Rectosigmoid | 2 |
| Detecting active inflammation (compared with biopsy or surgical excision histology): | |
| Accuracy | 86.7%* (46/53; P < 0.001) |
| Sensitivity | 90.0% |
| Specificity | 82.6% |
| Detecting mural fibrosis (overall, compared with surgical excision histology): | |
| Accuracy | 64.9% (24/37; P = 0.082) |
| Sensitivity | 58.3% |
| Specificity | 76.9% |
| Detecting mural fibrosis (excluding cases with co-existing active inflammation): | |
| Accuracy | 88.2%* (15/18; P = 0.013) |
| Sensitivity | 83.3% |
| Specificity | 83.3% |