Table I.

Competitive Antibody Binding

MAb competitor	Binding	Ability to block HuEP binding to
		P-selectin	E-selectin
G1	P-selectin	−	−
HAE	E-selectin	−	−
WAPS12.2	P-selectin	+	−
BBIG-E4	E-selectin	−	+

Table of competitive antibody binding against HuEP microbeads to map specific adhesion epitope. All antibodies are function blocking against the respective selectin target. The ability to block HuEP binding to P-selectin or E-selectin is indicated by a “+” and measured by introducing the competing antibody to the selectin surface before introducing microbeads coated with HuEP.