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Tumor-to-muscle ratios derived from the biodistribution studies.
| compound | tumor-to- muscle ratio |
Relative ratio compared to compound 11 |
|---|---|---|
| Ac-TZ14011-DTPA (11) | 6.67 ± 0.66 | 1 |
| monomer Ac-TZ14011-MSAP (3) | 4.55 ± 0.68* | 0.68 |
| dimer (Ac-TZ14011)2-MSAP (7) | 7.41 ± 1.87 | 1.11 |
| tetramer (Ac-TZ14011)4-MSAP (10) | 5.47 ± 0.50 | 0.82 |
P < 0.05 for the comparison of compound 3 with 11.
