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. Author manuscript; available in PMC: 2013 Jul 15.
Published in final edited form as: Curr Biol. 2012 Nov 20;22(22):R951–R953. doi: 10.1016/j.cub.2012.10.004

Fig. 1.

Fig. 1

Utilization of stored histone proteins and mRNAs in Drosophila embryogenesis. A. Unfertilized eggs there are stored histone proteins - H3 and H4 bound to a nucleoplasmin-like histone chaperone, and H2a/H2b bound with Jabba in lipid droplets, as well as stored histone mRNAs. B. In the wild-type embryos most of the histone incorporated into chromatin come from the stored histone proteins. C. In Jabba mutant embryos, there is no stored histone H2a/H2b and these proteins are synthesized from the stored maternal histone mRNAs. D. In Jabba, SLBP mutant embryos where there is a slightly reduced (~50%) amount of stored histone mRNAs there are not sufficient histone H2a and H2b synthesized for appropriate assembly of chromatin and the embryos die.