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. Author manuscript; available in PMC: 2013 Jul 15.
Published in final edited form as: J Neurochem. 2012 Jan 23;120(5):779–794. doi: 10.1111/j.1471-4159.2011.07620.x

Figure 2.

Figure 2

Effects of DAMGO pretreatment on methamphetamine-induced zif/268 mRNA expression in the rostral striatum, 45 minutes post-treatment. In situ hybridization films (A) showing zif/268 mRNA expression in the rostral striatum. Note the enhanced zif/268 mRNA expression, as well as the homogenous pattern of expression in DAMGO-pretreated, methamphetamine-treated animals. Quantitative analysis of zif/268 mRNA expression in the patch and matrix compartments of dorsolateral (B), dorsomedial (C), ventrolateral (D) and ventromedial (E) striatum, from rats intrastriatally infused with vehicle or DAMGO (1 μg/μl) 15 minutes prior to treatment with methamphetamine (0.5 mg/kg). Quantitative values are average gray values (arbitrary units, ±SEM, n=5–8 animals). *Significantly different from vehicle-pretreated control group, P<0.05; +Significantly different from vehicle-pretreated methamphetamine-treated group, P<0.05. There was a significant overall main effect of methamphetamine treatment in the patch and matrix compartments of ventromedial striatum.