Table 4.
Males (n=13) | Females (n=12) | p-value* | |||
---|---|---|---|---|---|
Visit 1 | Visit 2 | Visit 1 | Visit 2 | ||
Glucose AUC (mL/dL/day) | 151207 ± 15936 | 146130 ± 8433 | 149480 ± 9046 | 150585 ± 8985 | 0.3954 |
Insulin AUC (uU/mL/day) | 21417 ± 12436 | 22505 ± 9041 | 25989 ± 12489 | 30310 ± 13798# | 0.0446 |
C-peptide AUC (nmol/L/day) | 1190 ± 445 | 1225 ± 424 | 1277 ± 413 | 1403 ± 538 | 0.1664 |
hGH AUC (ng/mL/day) | 2824 ± 1795 | 1449 ± 1283# | 3414 ± 2294 | 3731 ± 2610 | 0.2157 |
Fasting Leptin (ng/mL) | 2.6 ± 1.7 | 5.0 ± 3.0# | 12.9 ± 4.9 | 21.9 ± 8.3# | <0.0001 |
Ghrelin AUC (pg/mL/day)^ | 236423 ± 1219322 | 146130 ± 8433 | 210260 ± 96529 | 220291 ± 76834 | 0.3559 |
Norepinephrine AUC (pg/mL/day) | 53767 ± 20500 | 48540 ± 12821 | 66303 ± 30198 | 61125 ± 29753 | 0.2940 |
Epinephrine AUC (pg/mL/day) | 4786 ± 2133 | 4938 ± 3405 | 6112 ± 5155 | 4695 ± 2861 | 0.3026 |
AUC = area-under the curve
P-value by paired t-test for all subjects combined (visit 1 vs visit 2)
Acylated (active) ghrelin
p<0.05 visit 2 vs visit 1 by sex