Figure 7.

Behavioral observations for the delayed reinstatement and between Lenti-mGluR₂- and Lenti-EGFP-injected animals in responding for natural rewards and in locomotor activity. A, We did not find time-dependent spontaneous recovery of lever pressing when reexposing the animals to the operant chamber after the 1 week time delay between last extinction trial followed by sham operation and reinstatement test. No differences were observed between Lenti-mGluR₂- and Lenti-EGFP-injected animals in responding for natural rewards and in locomotor activity. B, Both groups were exposed to five 30 min operant sessions to self-administered sweetened condensed milk under an FR1 schedule. Lenti-mGluR₂ and Lenti-EGFP lever-pressing behavior did not differ. C, Lenti-mGluR₂ and Lenti-EGFP rats show equal locomotion when exposed to a 45 min open-field session. Inset, Total track length completed in the 45 min session. Error bars indicate SEM.