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Meis1 is transcriptionally downstream of Pbx1. (A) Bar graph shows Pbx1 and Meis1 transcript levels in GMPs relative to CMPs measured by real-time PCR on progenitors freshly isolated from wild-type BM cells (*P≤0.002). (B) Bar graph shows Pbx1 and Meis1 transcript levels measured by real-time PCR either on freshly isolated wild-type c-Kit+ cells (day 0), or from cultured cells before (day 1) or after (day 3) transduction with a retroviral vector encoding Pbx1 (*P≤0.0007).
